Researchers at CaaMTech, the University of Massachusetts Dartmouth, and Canopy Growth USA have published an article in ACS Omega detailing the synthesis, crystal structure, and serotonin receptor activity of 4-HO-TMT (4-hydroxy-N,N,N-trimethyltryptamine).1 This paper is the latest in a series of from CaaMTech that have come out since early 2019.2–10
Chadeayne et al. explained that their impetus for this study was gaining a better understanding of other potentially psychoactive molecules in magic mushrooms (aka psilocybin mushrooms) besides psilocin. They noted that the literature indicates the effects of magic mushrooms are different from pure psilocybin, suggesting a synergy such as what occurs between the compounds in cannabis.11,12 Chadeayne et al. stated, “The extracts of ‘magic mushrooms’ demonstrate the same clinical effects as pure psilocybin at dosages that are an order of magnitude smaller, suggesting important activity by other psychoactive molecules or the presence of an entourage effect.”
4-HO-TMT is purportedly the metabolite of aeruginascin
Re: Entheobotanik-Stammtisch
Verfasst: 8. Jul 2020, 18:41
von Arkan
Gaius hat geschrieben: ↑8. Jul 2020, 18:31
Ein neuer psychedelischer Pilz / Entheogen wurde entdeckt:
Study Finds Aeruginascin Metabolite 4-HO-TMT is Active at the Serotonin 5-HT2A Receptor
Von Barbara E. Bauer
Researchers at CaaMTech, the University of Massachusetts Dartmouth, and Canopy Growth USA have published an article in ACS Omega detailing the synthesis, crystal structure, and serotonin receptor activity of 4-HO-TMT (4-hydroxy-N,N,N-trimethyltryptamine).1 This paper is the latest in a series of from CaaMTech that have come out since early 2019.2–10
Chadeayne et al. explained that their impetus for this study was gaining a better understanding of other potentially psychoactive molecules in magic mushrooms (aka psilocybin mushrooms) besides psilocin. They noted that the literature indicates the effects of magic mushrooms are different from pure psilocybin, suggesting a synergy such as what occurs between the compounds in cannabis.11,12 Chadeayne et al. stated, “The extracts of ‘magic mushrooms’ demonstrate the same clinical effects as pure psilocybin at dosages that are an order of magnitude smaller, suggesting important activity by other psychoactive molecules or the presence of an entourage effect.”
4-HO-TMT is purportedly the metabolite of aeruginascin